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Stroke: The relationship between trimethylamine nitroxide and stroke recurrence depends on the subtype of ischemic stroke

 Last Update: 2021-12-03
 Source: Internet
 Author: User

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Trimethylamine N- oxide (of TMAO) has been recognized as a cardiac vascular disease risk factors

Heart vascular stroke

The study included a total of 10,756 patients with ischemic stroke/transient ischemic attack from the Third China Stroke Registration Center.

In the multivariate Cox regression model, elevated TMAO levels were independently associated with the risk of stroke recurrence (Q4 and Q1: adjusted hazard ratio was 1.

After stratification by TOAST subtype, there was a significant association between TMAO and stroke recurrence in the arteriolar occlusion subtype (adjusted hazard ratio 1.

It can be seen that elevated TMAO levels are associated with an increased risk of stroke recurrence in patients with small artery occlusion subtypes, but this association seems to be weakened in large artery atherosclerosis, cardiogenic embolism, and other subtypes

Elevated TMAO levels are associated with an increased risk of stroke recurrence in patients with small artery occlusion subtypes, but this association seems to be weakened in large artery atherosclerosis, cardiogenic embolism, and other subtypes

Original source:

Jie Xu.

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