Sudden reduction of white blood cells

On May 1, 84-year-old Grandmother Chen, who was picked up by 120 first aid, was admitted to hospital after not eating for two days of persistent low feverBody: Body temperature 37.8 degrees of the doctor immediately requested blood check routine , the results show that the WBC: 11.87 x 10 ? 9 / L Neu%: 92.9 LYM%: 4.0 CRP: 18.1mg/LOn the same day the doctor prescribed the doctor's instructions for cephalosporin, vitamin C and other drugs for treatmentThe next day, patients were asked to re-review the blood routine and CRP, liS system tips compared to historical results, and found that WBC: 4.21 x 10?9/L Neu%: 78.1 LYM%:12.5 CRP: 42.5mg/Lsaw the result, the thought is why the two-day results are so different? Does CRP continue to rise after medication? So I immediately check the status of the instrument, reagents, and quality control, sample status, and patient information are not abnormal!what's wrong withso? With doubt, I reviewed Grandma Chen's two-day specimen and the results were not much different from the previous resultsThen I also communicated with Grandma Chen's stewards, asking about the patient's detailed medical history, and learned that the patient had dialed 120 emergency calls because of two days of fever, not eating, and a mild comain order to solve my doubts, I opened the book of internal medicine: in the bone marrow for stem cell pool (pluripotent hematopoietic stem cell a line of targeted progenitor cells), division pool (primitive granulocytes - mid-baby granulocytes), storage pool (late granulocytes - mature granulocytes)Mature neutrophils are stored in the bone marrow, 8-10 times the size of the blood, and can be released into the blood at any timeAfter neutrophils arrive in the blood, half are attached to the small blood vessel wall, called the edge pool, and the other half is in the blood circulation, called the circulatory poolwe are detecting changes in the number of cells in the circulatory pool, and the cells in the edge and circulating pools are balancedPathological factors such as poisoning and infection can break this balanceBecause the patient's infection is more severe, it causes white blood cells to attach to the inner wall of the blood vessels, resulting in a significant reduction in the cell count of the circulating poolMay 4, the patient due to physical improvement request discharge, the doctor again asked the patient to review the blood routine , CRP results show edified WBC: 3.36 x 10 ? 9 / L Neu%:65.7 LYM%:23.5 CRP: 6.6mg/L blood image is basically normalAllow him to be discharged from the hospitalSummaryin our usual work, encountered abnormal results, to timely active communication with the clinical, understand the actual situation of patients and make accurate and timely judgmentAs a tester, we should strengthen the study of professional knowledge and update your knowledge baseMake sure that every report you send is correctSource: