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    Home > Active Ingredient News > Blood System > Support Care Cancer: Thrombosis and catheter-related bloodstream infections are significant complications of CVC in AML patients

    Support Care Cancer: Thrombosis and catheter-related bloodstream infections are significant complications of CVC in AML patients

    • Last Update: 2022-02-18
    • Source: Internet
    • Author: User
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    Central venous catheters (CVCs) are widely used in patients with acute myeloid leukemia (AML)
    .
    Complications associated with CVC are frequently encountered and contribute to morbidity and mortality
    .
    Prospective studies investigating and comparing different types of CVC complications in AML patients and their impact on quality of life are limited
    .
    A research team conducted a prospective observational study to assess complications associated with CVC use during induction chemotherapy in adult AML patients and to assess patient-reported quality of life outcomes during and after hospitalization


    .


    Central venous catheters (CVCs) are widely used in patients with acute myeloid leukemia (AML)


    Figure 1: Patient-reported experiences and activities related to CVC
    .
    Mean scores on questionnaires administered to patients 2 weeks after CVC placement and 90 days after discharge
    .
    Results were compared with the Wilcoxon rank sum test
    .
    TCC, tunneled central catheter; PICC, peripherally inserted central catheter
    .

    Figure 1: Patient-reported experiences and activities related to CVC
    .
    Mean scores on questionnaires administered to patients 2 weeks after CVC placement and 90 days after discharge
    .
    Results were compared with the Wilcoxon rank sum test
    .
    TCC, tunneled central catheter; PICC, peripherally inserted central catheter
    .

    Table 1: Characteristics of patients

    Table 1: Characteristics of patients

    Table 2: Complications associated with CVC in AML patients The results show that 50 newly diagnosed AML patients (median age, 59 years) receiving intensive induction chemotherapy were included in the study


    .
    A peripherally inserted central catheter (PICC) was placed in 29 patients (58%) and a Hickmann tunneled central catheter (TCC) was placed in 21 (42%) patients


    Table 2: CVC-related complications in AML patients Fifty newly diagnosed AML patients (median age, 59 years) receiving intensive induction chemotherapy were included in the study .
    A peripherally inserted central catheter (PICC) was placed in 29 patients (58%) and a Hickmann tunneled central catheter (TCC) was placed in 21 (42%) patients .
    Catheter-related thrombosis occurred in 3% of cases in PICC but not in TCC .


    Original source:

    Original source:

    McKeown, C.


    , Ricciuti, A.
    , Agha, M.


    McKeown, C.
    , Ricciuti, A.
    , Agha, M.
      et al.
     A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy.
      Support Care Cancer 30,  1673–1679 (2022 ).
    https://doi.
    org/10.
    1007/s00520-021-06339-x  McKeown, C.
    , Ricciuti, A.
    , Agha, M.
      et al.
     A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy.
      Support Care Cancer 30,  1673–1679 (2022).
    https://doi.
    org/10.
    1007/s00520-021-06339-x Leave a comment here 

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