echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > Targeting mitochondria is expected to treat obesity!

    Targeting mitochondria is expected to treat obesity!

    • Last Update: 2021-08-28
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    A high-fat diet can lead to obesity and metabolic disorders such as diabetes and fatty liver


    Elaborate genetic studies in mice have shown that keeping the mitochondrial network in a fused state can overcome obesity caused by a high-fat diet


    In their new research, Professor Edinger and her team used their patented water-soluble, oral bioavailability, synthetic sphingolipid SH-BC-893 to inhibit the endolysosomal transport protein required for mitochondrial fission


    "The imbalance of leptin and adiponectin hormones that accompanies obesity has brought a difficult battle for people who want to lose weight


    The results of this study indicate that SH-BC-893 may be a promising treatment for diet-induced obesity


    Professor Edinger said: "This compound works through a new mode of action-if it is safe and effective for humans, it will provide a new weight loss strategy and can also be combined with other treatments


    Journal Reference :

    1. Vaishali Jayashankar, Elizabeth Selwan, Sarah E Hancock, Amandine Verlande, Maggie O Goodson, Kazumi H Eckenstein, Giedre Milinkeviciute, Brianna M Hoover, Bin Chen, Angela G Fleischman, Karina S Cramer, Stephen Hanessian, Selma Masri, Nigel Turner, Aimee L Edinger.



    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Related Articles

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.