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    Home > Active Ingredient News > Blood System > The cause of anemia is too complex, these 3 tests are easy to identify!

    The cause of anemia is too complex, these 3 tests are easy to identify!

    • Last Update: 2020-09-01
    • Source: Internet
    • Author: User
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    Anemia is a clinical syndrome that causes the volume of erythrical red blood cells to be lower than normal for a variety of reasons.
    red blood cell count, hemoglobin volume, and red blood cell pressure in circulating blood with a certain volume are lower than normal.
    hemoglobin is the most important of these.
    epidemiological status of anaemia The World Health Organization (WHO) regularly selects bone marrow morphological examinations based on the 1993-2005 WHO Vitamin and Mineral Nutrition Information System estimates the main means of differential diagnosis of clinical anemia.
    but the method is traumatic and the results of the examination are susceptible, so it is limited in practical application.
    recent years, serological indicators of anemia have been widely used in anemia diagnosis, including hemoglobin (SF), folic acid (FA), vitamin B12 (VB12) testing.
    case of three clinical applications of anemia, one patient, female, 47 years old, dizziness, fatigue, total blood cell reduction of six months.
    : mild anemia appearance, skin around no rash, yellow dye, bleeding point, shallow lymph nodes no swelling.
    no congestion in the pharynx and no swelling in the tonsils.
    "Blood routine" (biochemical examination) "bone marrow biopsy" bone marrow growth is more active, the proportion of red line increased, mainly in the middle and late red, mature red blood cells vary in size, mainly small cells, the center of the expansion of the dyeing area.
    the "Anemia Tri-Examination" (Diagnosis) Iron Deficiency Anemia.
    is treated with iron supplementation.
    case two patients, female, 34 years old, panic, shortness of breath, intermittent low heat, weak lower limbs for more than three months.
    Examination: severe anemia appearance, skin around the skin without rash, yellow dye, bleeding point, the left jaw can touch the swollen lymph nodes several pieces, 1.5 x 1.5cm size, quality toughness, activity can, light pressure pain.
    conjunctivation is pale and the scleum is yellow-stained.
    "Blood routine" (biochemical examination) "bone marrow biopsy" bone marrow growth is more active, the proportion of red line increased, the grain system infant stage cells increased, to the middle and young and below stage cells mainly, red line to middle and late red-based, visible giant young-like cells.
    "Three Examinations of Anemia" (Diagnosis) Giant Young Cell Anemia (Treatment) The case study of VitB12 intramuscular injection every other day can be seen in a variety of diseases, the eeries are different, and its treatment options are not the same.
    according to the blood routine reports in both cases, they all had clear anemia, but eeriological indicators showed different types of anemia.
    case one is iron deficiency anemia caused by iron deficiency, which requires iron supplementation treatment.
    case two is vitamin B12 deficiency caused by giant larvae anemia, vitamin B12 supplementation is needed for treatment.
    It is necessary to correctly identify and distinguish between different types of anemia, iron deficiency anemia and giant larvae anemia are among the most common types of anemia, so the detection of anemia is extremely valuable in clinical diagnosis and treatment.
    And, in other anemia diseases that are easily confused with iron deficiency anemia or giant larvae anemia (e.g. iron granulocytic anemia, thalassemia, bone marrow growth abnormal syndrome, etc.), the three anemias are also of great significance for differential diagnosis.
    , in some acute leukemias that require bone marrow testing, anemia is also of secondary diagnostic value.
    , anemia is also an important indicator to assess the severity of the disease and observe its efficacy, which needs to be monitored dynamically.
    present, the detection of anemia three serological indicators has the advantages of fast, non-traumatic, economic, sensitive, accurate, early diagnosis, etc., has been more and more widely used in clinical.
    the clinical significance of the three tests for anemia.
    01 iron protein (SF) ferroprotein is a brown iron-containing protein complex that is mainly synthesized in the liver.
    it reflects the total amount of iron stored in the liver and the nutritional status of the body, and is an effective index for detecting iron deficiency and excessive iron load diseases.
    that the timely determination of ferroprotein is important for the prevention of anemia due to iron deficiency before it occurs.
    guidelines for diagnosis and treatment of iron deficiency and iron deficiency anemia during pregnancy in 2014 recommend that serum iron protein concentrations be sl;20 ?g/l to diagnose iron deficiency.
    (Reference Interval) Male: 23.9 - 336.2 ng/ml Female: 11.0 - 306.8 ng/ml Increase Is common in: (1) increase in iron storage in the body: primary hemochrome disease, secondary iron load is too high.
    (2) increase in ferroprotein synthesis: inflammation, tumors, leukemia, hyperthyroidism, etc.
    (3) anemia: hemolytic anemia, regenerative anemia, malignant anemia.
    (4) tissue release increased: liver necrosis, chronic liver disease and so on.
    are common in iron deficiency anemia, hemolytic anemia, chronic anemia, chronic diarrhea, malnutrition, etc.
    02 folic acid (FA) folic acid is a compound made up of arginine, amino benzoic acid and glutamate, which are essential essential vitamins for normal cell growth and DNA synthesis.
    widely found in a variety of foods, such as dark leafy vegetables, citrus fruits, yeast, beans, eggs, and milk.
    folic acid is absorbed by the small intestine and stored in the liver.
    6.8 nmol/L deficiency is common in cytological cells or giant red blood cell anemia and leads to neuropathological disorders.
    malignant disorders (lung cancer, bowel cancer, etc.) and kidney anemia.
    03 Vitamin B12 (VB12), also known as cobaltamine, consists of a tetrin ring around a structure centered on cobalt atoms.
    cobaltamine can be found in animal products such as meat, eggs, milk and other dairy products.
    ingestion, cobaltamine is combined with a protein called an internal factor in the stomach fluid, which is then absorbed into the blood circulation in the intestinal tract and stored in the liver.
    133-675 pmol/L increase is found in: bone marrow growth abnormal syndrome, chronic granulocytic leukemia, true red blood cell growth, various types of liver disease, etc.
    deficiency is common in: giant larvae anemia, stomach mucous membrane "inner factor" protein deficiency to the malignant anemia, malignant tumor caused by secondary anemia.
    other such as gastroenterology, gastroenterology, enteritis, long-term vegetarians are affected by B12 absorption, ingestion, so that B12 reduced.
    "Project Advantage" Murray chemical luminescent anemia test kit Myri anemia project advantage iron protein project fits the reference range of group Chinese, accurate clinical compliance rate.
    folic acid: supports serum/plasma sample testing, and the same reagent is calibrated once to detect serum/red blood cell folic acid.
    VB12: efficient anti-similar interference capability, providing detection accuracy;
    Zhu Guoqing, Director of the Clinical Testing Center of the Hematology Hospital of the Chinese Academy of Medical Sciences.
    has been engaged in medical examination for nearly two decades and asset management for three years, and has extensive experience in clinical laboratory management, clinical immunology and clinical microbiology.
    Standing Committee member of the Clinical Engineering Society branch of the China Medical Equipment Association, first standing member of the medical laboratory construction and management group of the medical clean equipment engineering branch of the Chinese Medical Equipment Association, member of the sixth professional committee of clinical medical engineering of the Tianjin Biomedical Engineering Society, member of the POCT branch of the Chinese Medical Device Industry Association, and member of the inspection physician branch of the Tianjin Physicians Association.
    source: Test medical network !-- the end of the content display -- !-- to determine whether the login ends.
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