 Home > Active Ingredient News > Blood System > The gospel of the Cilantro Party?

The gospel of the Cilantro Party?

 Last Update: 2021-09-19
 Source: Internet
 Author: User

Tags

causes infectious diseases

endometriosis pain treatment

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Leukemia is a group of heterogeneous blood diseases characterized by the uncontrolled and dysfunctional growth of white blood cells

Plants are an inexhaustible source of biologically active substances

Diabetes Digestion

Previous studies on animal models have shown that several compounds in the figure above have a wide range of cancer prevention and chemotherapy properties, and various approaches may be related to perfect synergy

prevention

In this study, 3 cell lines- human acute promyelocytic leukemia (HL60), human chronic myelogenous leukemia (K562) and normal Luo cells-were used to evaluate CSP polyphenol extracts:

Human acute promyelocytic leukemia

As shown in the figure above, the extract can inhibit the spread of HL60 (IC50 = 11.

After K562 cell line was treated with 25μg/mL and HL60 cell line at 12μg/mL for 24 h, the number of viable cells was significantly reduced by 50%.

Within 14 days after CSP extract treatment, no signs of death or poisoning of experimental animals were found, and a single oral administration of 2000 mg/kg body weight of CSP extract did not interfere with the growth of mice

In this study, four receptors (ABL kinase, ABL1, BCL2, and FLT3) that are highly concerned in anti-leukemia research and treatment were selected as targets:

The reference drug navitoclax has the highest affinity to the receptor (-11.

The drug navitoclax has the highest affinity to the receptor (-11.

In summary , this study shows that the anti-leukemia activity of CSP extract comes from the synergistic anti-cancer effect of catechin and rutin molecules
.
The anti-leukemia activity of
plant CSP extracts comes from the synergistic anti-cancer effect of catechin and rutin molecules .
Plant extracts have strong activity and fewer side effects, or can be used as a supplement or replacement for conventional treatment and chemotherapy
.

Leave a message here

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.