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*For medical professional reading reference only
Don't forget to ask the patient's medication history!
Osteoporosis (OP) is a systemic bone metabolic disorder characterized by low bone mineral content, damage to bone microstructure, and reduced bone strength, resulting in increased bone fragility and susceptibility to fractures
The anticoagulant - warfarin
Warfarin can inhibit the carboxylation of osteocalcin and reduce bone calcium deposition, thereby interfering with bone metabolism, leading to osteoporosis or fractures, and the risk of long-term use is greater
3.
Thiazolidinediones (TZDs) are a new class of drugs that increase insulin sensitivity.
The proton pump inhibitor - omeprazole
Proton pump inhibitors (PPIs) are commonly used drugs for peptic ulcer.
Summarize
Drug-induced osteoporosis (DIO) seriously affects the quality of life of patients, easily causing falls, fractures and even life-threatening.
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A systematic review of the effect of proton pump inhibitors on fracture risk [J].
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[7] Hou Jianming, Li Jianwei, Lin Qingming, et al.
Changes of bone mineral density in patients with type 2 diabetes mellitus complicated with peripheral vascular disease.
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[8] Zhao Liwei, Liu Gaifang, Wu Jing, etc.
Long-term application of proton pump inhibitors in elderly patients affects bone density Research on the influence of porosity[J].
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[9] Cai Ying, Cong Xu, Fei Ran.
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This article was first publishedResponsible Editor of Drug Evaluation CenterCao Qian
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