The team of Professor Lin Songyi of Dalian University of Technology: Matsutake-derived protein active peptide has obvious protective effect on ethanol-induced acute gastric injury

Recently, Professor Lin Songyi from the National Marine Food Engineering Technology Research Center of Dalian University of Technology has made important research progress in the development of functional activity of matsutake-derived protein peptides and found that matsutake-derived protein active peptides have obvious preventive effects on ethanol-induced acute gastric injury.

The mucosa of the gastrointestinal tract communicates directly with the outside world, and is prone to damage and lesions

Paper pictures

The study found that Matsutake-derived protein active peptides SDIKHFPF and SDLKHFPF can significantly promote the proliferation of GES-1 cells, inhibit the apoptosis of GES-1 cells, effectively improve the symptoms of acute gastric injury caused by ethanol, significantly reduce gastric mucosal pressure and ulcer index, and protect gastric glands.

Matsutake-derived protein active peptides SDIKHFPF and SDLKHFPF induce tissue reconstruction by inhibiting the release of inflammatory factors and promoting the expression of growth factors, thereby accelerating the recovery of gastric mucosa and achieving the effect of protecting gastric mucosa

To further analyze the mechanism of matsutake-derived protein active peptide in protecting acute injury caused by ethanol