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    Home > Active Ingredient News > Endocrine System > Thyroid: Comparing the effects of antithyroid drugs and vitamin D supplementation on the muscles and quality of life of patients with Graves disease

    Thyroid: Comparing the effects of antithyroid drugs and vitamin D supplementation on the muscles and quality of life of patients with Graves disease

    • Last Update: 2021-09-19
    • Source: Internet
    • Author: User
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    Background: Vitamin D deficiency is believed to play a role in the development and progression of Graves disease (GD)


    Muscle weakness and reduced quality of life (QoL) are common features of GD and vitamin D deficiency


    Results: 9 months after vitamin D supplementation, the increase in muscle strength in all muscle indicators was weakened, especially when the knee joint was extended at 60°.


    Table 1 The effect of vitamin D supplementation for 9 months on changes in body composition

    Table 1 The effect of vitamin D supplementation for 9 months on changes in body composition

    Table 2 Changes in physical performance and body composition of patients with Graves disease during 9 months of treatment with antithyroid drugs

    Table 2 Changes in physical performance and body composition of patients with Graves disease during 9 months of treatment with antithyroid drugs

    Conclusion: Vitamin D supplementation for 9 months has an adverse effect on the recovery of muscle function


    Supplementing vitamin D for 9 months has an adverse effect on the recovery of muscle function


     Grove-Laugesen D, Cramon PK,et al, Effects of Supplemental Vitamin D on Muscle Performance and Quality of Life in Graves' Disease: A Randomized Clinical Trial.


    Effects of Supplemental Vitamin D on Muscle Performance and Quality of Life in Graves' Disease: A Randomized Clinical Trial.


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