echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Blood System > Thyroid: The effect of thyroid function on hemostasis, coagulation and fibrinolysis systems

    Thyroid: The effect of thyroid function on hemostasis, coagulation and fibrinolysis systems

    • Last Update: 2021-11-03
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Background: Untreated hypothyroidism is associated with acquired von Willebrand syndrome, and hyperthyroidism is associated with an increased risk of thrombosis


    Untreated hypothyroidism is associated with acquired von Willebrand syndrome, and hyperthyroidism is associated with an increased risk of thrombosis


    Results: The increase of TSH gene is related to the decrease of VWF [β(SE)=-0.


    Figure 1 Mendelian randomization of thyroid function VWF, FVIII and APTT


    Figure 1 Mendelian randomization of thyroid function VWF, FVIII and APTT


    Figure 2 Mendelian randomization of fibrinogen, PT and FVII by thyroid function


    Figure 2 Mendelian randomization of fibrinogen, PT and FVII by thyroid function


    Figure 3 D-Mendelian randomization study of dimer, PAI-1 (plasminogen activator inhibitor) and tissue plasminogen activator (TPA) on thyroid function shows that it is based on the inverse variance weighted random effect Analysis


    Figure 3 D-Mendelian randomization study of dimer, PAI-1 (plasminogen activator inhibitor) and tissue plasminogen activator (TPA) on thyroid function shows that it is based on the inverse variance weighted random effect Analysis


    In the largest genetic study at present, the increase of TSH and fT4 genes may be related to the decrease and increase of VWF synthesis, respectively


    Ellervik C, Mora S, Kuś A,et al.


    Effects of thyroid function on hemostasis, coagulation , and fibrinolysis: a Mendelian Randomization study

    in this message
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.