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Treating a variety of neurological diseases about 2.6 billion US dollars to help develop selective GPCR agonists

 Last Update: 2021-12-04
 Source: Internet
 Author: User

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Recently, Neurocrine Biosciences and Sosei Heptares announced a strategic cooperation and licensing agreement to jointly develop new selective muscarinic receptor agonists for the treatment of schizophrenia, dementia and other neurological diseases

Muscarinic receptors are essential for brain function and have been verified as drug targets for psychosis and cognitive impairment

Based on this platform, the company has discovered a variety of selective muscarinic M4, M1 and M1/M4 dual agonists, which have potential therapeutic effects while avoiding the harmful side effects caused by non-selective agonists

According to the agreement, Neurocrine Biosciences will obtain the right to develop and commercialize the new selective muscarinic M4, M1 and dual M1/M4 receptor agonists discovered by Sosei Heptares

In addition to the M1 agonist being developed in Japan, Neurocrine Biosciences will be responsible for development costs related to global R&D projects

Reference materials:

[1] Neurocrine Biosciences and Sosei Heptares Announce Collaboration to Develop Novel Muscarinic Receptor Agonists for Schizophrenia and Other Neuropsychiatric Disorders.

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