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    Home > Active Ingredient News > Blood System > Universal CAR-NK for relapsed/refractory B-cell lymphoma, 3/6 cases achieved CR

    Universal CAR-NK for relapsed/refractory B-cell lymphoma, 3/6 cases achieved CR

    • Last Update: 2022-05-25
    • Source: Internet
    • Author: User
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    On April 25, U.


    On April 25, U.


    NKX019 is a CD19-targeting CAR-NK cell therapy from Nkarta and a "universal" CAR-NK cell therapy


    Lymphoma leukemia high-dose (10x10 8 CAR-NK cells, 3 infusions) group, of 6 evaluable patients: 5 achieved objective response (ORR=83%), 3 achieved complete response (CR=50%) , including one patient with diffuse large B-cell lymphoma and one patient with mantle cell tumor


    Likewise, no dose-limiting toxicities, as well as adverse events similar to the side effects of CAR-T


    CAR-T

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