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Viruses-Basel: Long-term outcomes after vaccine-induced thrombotic thrombocytopenia

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Vaccine-induced thrombotic thrombocytopenia (VITT) or thrombosis with thrombocytopenia syndrome (TTS) is a rare but serious complication

This single-center, continuous cohort study included all vaccinations based on (1) vaccination 4 to 21 days prior to symptom onset, (2) signs or symptoms of venous or arterial thrombosis, (3) thrombocytopenia < 150/nL, (4) antiplatelet factor 4 (PF4) antibody positive, and (5) elevated D-dimer > 4 times

Figure 1: D-dimer and platelet counts

Figure 2: D-dimer for individual patients

Eculizumab was successfully used in two patients with

In summary, VITT appears to be a highly prethrombotic lesion

Original Source:

Panagiota V, Dobbelstein C, Werwitzke S, Ganser A, Cooper N, Sachs UJ, Tiede A.

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