What should I pay attention to when choosing an injection to supplement vitamin D?

*For medical professionals only

Director Bian Pingda of Zhejiang Provincial People's Hospital published the 59th article

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Who needs vitamin D supplementation?

Vitamin D supplementation, why choose injections?

Although the calcium tablets that are often taken by middle-aged and elderly people currently contain a certain amount of vitamin D, their content is extremely low

Each injection of 600,000 IU, will the dose be too large?

The first thing to note is that 600,000 IU per injection of vitamin_D2 is the normal dose of vitamin D2 injections

Why is mass spectrometry recommended to monitor the efficacy of vitamin_D2 injections?

Studies have shown that after intramuscular vitamin_D2 injection, serum 25(OH)_D2 levels gradually increase and 25(OH)_D3 levels decrease significantly^[3], see Figure 1

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Guidelines for the Application of Vitamin D and Bone Health in Adults (2014 Standard Edition)[J].
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[2] Bian Pingda, Li Jianying, Wu Huiying, et al.
Effect of vitamin D2 injection on serum parathyroid hormone in elderly men with vitamin D deficiency[J].
Chinese Journal of New Drugs and Clinical Journal,2021,40(6):328-332.
[3] Bian PD，Jin X，Shou Zh X.
Effects of monthly intramuscular high-dose vitamin D2 on serum 25-hydroxyvitamin D and immune parameters in very elderly Chinese patients with vitamin D deficiency[J].
Int J Endocrinology，2021，1343913.
[4] Li L，Zeng Q，Yuan J，et al.
Performance evaluation of two immunoassays for 25-hydroxyvitamin D[J].
J Clin Biochem Nutr.
2016，58(3):186-192.