Why can't human albumin be infused too quickly?

reason

Reason one

When a large amount of albumin is infused, the protein content in the plasma suddenly rises, which causes the plasma colloidal osmotic pressure to rise, and the water in the interstitial space flows into the blood vessels in a large amount, resulting in tissue dehydration.

Reason two

Albumin accounts for 80% of plasma colloidal osmotic pressure, which mainly regulates the dynamic balance of water between tissues and blood vessels.

Precautions for human albumin transfusion

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People who are contraindicated with human albumin

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How to use human albumin

Human albumin generally has injections, freeze-dried powder injections, intravenous boluses, and intravenous drips.

Dosage:

(1) Shock caused by severe burns or blood loss: direct injection of 5-10g, repeat once every 4-6h;

(2) Chronic albumin deficiency such as nephropathy and liver cirrhosis: Inject 5-10g daily until the edema disappears and the serum albumin content returns to normal.

Compatibility taboo:

It is forbidden to mix with vasoconstrictors, proteolytic enzymes, protein hydrolysates, amino acid solutions or injections containing alcohol solutions.