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Introduction of commonly used carrier components and application of virus vectors
Time of Update: 2020-12-22
1. Common vector classification: 2, commonly used carrier element introduction: (1) initiators: initiators are located in the structure gene 5' side upstream of the DNA sequence, can activate the RNA polymerase, so that it is accurately combined with the template DNA and has the specificity of transcription starting.
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Gene knockout of Bacillus tuberculosis helps to study the signaling path path of cell coke death
Time of Update: 2020-12-22
results: 1, EST12 (Rv1579c) induced GSDMD-mediated macrophage coke death expression purification of 40 RD region coded proteins, through LDH release experiments, found that EST12 (Rv1579c) has significant macrophage toxicity.
smeg-EST12 experimental groups (Figure 2J) results are condensed: EST12 causes macrophage inflammatory coke death through RACK1.
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To prevent depression and become a master of emotional management, you may first have to have a good stomach
Time of Update: 2020-12-22
using animal models, the scientists found that changes in the gut microbiome caused by chronic stress can lead to depressive behavior, especially by causing a decrease in lipid metabolites (small molecules produced by metabolism) in the blood and brain.
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High blood sugar can lead to intestinal leakage and intestinal bacteria disorders
Time of Update: 2020-12-22
High blood sugar causes intestinal leakage To test whether elevated blood sugar levels were involved in regulating the function of the intestinal barrier, the researchers induced high blood sugar in mice without obesity, using a drug called streptococcus, which destroys islet β cells in mice, resulting in a phenomosis very similar to type 1 diabetes in humans.
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Zhang Peace Team: Probiotic-assisted treatment of IBS can relieve symptoms and reduce inflammation
Time of Update: 2020-12-11
。 1. IBS patients were randomly divided into probiotic group (24 cases) and control group (21 cases), respectively, to receive routine treatment with or without probiotics, 2. After 28 days of interv
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Messy bacteria, lead to wolves.
Time of Update: 2020-12-11
。 Zhang Wei guide students Recently, Beijing Concord Hospital rheumatology immunology professor Zhang Wei team in the United States Rheumatology Society's official journal Arthritis and Rheumatology
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The story between the baby and the probiotics
Time of Update: 2020-12-11
Especially with loss of appetite, constipation, frequent diarrhea or indigestion of the baby, long-term choice of probiotic yogurt can also regulate gastrointestinal function.
Probiotic-rich foods After your baby is 1 year old, you can eat some probiotic-rich foods every day, commonly yogurt, cheese, lactic acid drinks, etc., but do not overeat.
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The effect and improvement of probiotic Probio-Fit on intestinal bacteriobis in patients with irritable bowel syndrome (IBS).
Time of Update: 2020-12-11
。 Figure 3 (AB): A for the Shannon index analysis, B for the super 1 index analysis UniFrac weighted average distance of the main coordinate analysis found that the probiotic group and the control group intestinal bacterios group on the 7th day of treatment there is a significant difference (P x 0.004), this difference decreased to the 28th day, but still exists (P s 0.079).
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"Small" lactic acid bacteria help the dairy farming industry
Time of Update: 2020-12-11
Probiotic lactic acid bacteria by regulating the intestinal bacteria to alleviate cow mastitis project team established a special lactic acid bacteria resource bank for dairy health breeding, created a lactic acid bacteria screening technology and evaluation system based on cow intestinal bacteria and silage fermentation micro-habitat, developed a high density culture technology of lactic acid bacteria, the number of fermented liquid live bacteria increased to 20 billion CFU/mL.
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The body's ability to detoxify is also inseparable from the intestinal bacteria
Time of Update: 2020-12-11
In addition, animal studies have shown that gut microorganisms may play a role in the ability of polyphenol compounds quercetin and uctrin to affect levels of the liver or intestinal second-stage detoxifying enzymes.
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People with unhealthy guts should be aware of these five food triggers
Time of Update: 2020-12-11
Imbalances in the intestinal bacteribus can lead to damage to the intestinal wall and increased permeability, allowing more food that is not fully digested to enter the bloodstream, leading to round after round of antigen exposure, excessive immune responses, more food insatiability or allergies, and even overgrowth of pathogenic bacteria.
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Summary of information about strains and edible strains that can be used in food
Time of Update: 2020-12-11
food partner network collated and summarized edible bacteria related regulations, this summary information will be updated from time to time to supplement, only for the reference of netizens.
Updated until 26 October 2020.
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Infant intestinal bacteria or from multiple parts of the mother body
Time of Update: 2020-12-11
Fetal feces and amniotic fluid, birth channel fluid, breast milk cytospheric similarity is significantly higher than other mother-source samples, which indicates that the intestinal bacterial structure of early infants is closely related to the pre-birth living environment (amniotic fluid) and the temporary environment (birth channel) during childbirth, the fetus may be in the womb by swallowing amniotic fluid to obtain the original mother-sourced microorganisms.
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Intestinal bacterial disorders contribute to the development of colorectal cancer
Time of Update: 2020-12-11
intestinal bacterial disorders induce the production of tumor-related genetic toxins and metabolites, which in turn can lead to immune system dysfunction, promote and maintain inflammatory bowel disease, leading to colorectal cancer.
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Intestinal bacterial disorders can increase the risk of stroke and affect stroke outcomes
Time of Update: 2020-12-11
addition to triamide oxide, other studies have shown that patients have different gut bacteria depending on the risk of stroke.
Transplanting fecal bacteria from patients with higher SDI levels to sterile mice can lead to more severe brain damage and an increase in intestinal inflammatory T-cells.
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Winter diet small common sense to improve autoimmunity
Time of Update: 2020-12-11
common sense: high-quality protein protein is the main component of the body's cells, our immune system of course also need it to function properly.
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Mutations in the SLC26A3 gene affect the mechanisms of IBD risk
Time of Update: 2020-12-11
(1) In the DSS-induced colitis mouse model, the colon permeability of DRA knockout mice increased significantly, and the level of ZO-1, closed protein, E-calcium adhesive protein, etc. was significan
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Effect of probio-M8 on immune function of rats in immunosuppressive model
Time of Update: 2020-11-25
Rat serum IgA, IgG, IL-2, IL-6, IFN-γ and TNF-α levels Experimental Conclusions Clocal BifidoProbio-M8 can improve the percentage of lymphocytes and T lymphocytes in immunosuppressive model rats The proliferation capacity and the increase of IgA, IgG, IL-2, IL-6, IFN-γ and TNF-α content in the serum improve the cellular immunity, body fluid immunity and inherent immune response regulation, while promoting immunomodulation in immunosuppressive rats.
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Wang Wei's team at the School of Basic Medicine revealed a new mechanism for intestinal bacteria to participate in the onset of autism
Time of Update: 2020-11-25
recently, the team of Wang Wei of the Department of Medical Bioinsyntics of Peking University's School of Basic Medicine, in collaboration with the Kang Wei team of the Beijing Genomics Institute of the Chinese Academy of Sciences, published an article in the journal Science Advances , "A quasi-paired cohort strategy reveals the granted detoxifying function of microbes in the gut of autistic children".
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Zhang peace team to crack the mother-to-child microbiotic transmission mechanism
Time of Update: 2020-11-25
Analysis of bacteriosophology similarity based on OTU levels found that fetal feces and amniotic fluid, vaginal fluid, breast milk cytosus similarity is significantly higher than other maternal source samples, indicating that the intestinal bacteriostructure structure of early infants is closely related to their pre-birth living environment (amniotic fluid) and temporary living environment (birth pathway) during childbirth, the fetus may be in the womb by swallowing amniotic fluid to obtain the original mother-source microorganisms.
