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Science sub-journal: Developed a CAR combined screening method to determine the most effective CAR-T cells for cancer treatment
Time of Update: 2023-01-05
Now, in a new study, researchers from the University of California, San Francisco, have developed a new way to compare large numbers of CAR-T cells, each with slightly different molecular characteristics, to determine which CAR-T cells are most effective and durable against cancer 。 The results were published in the Nov. 9, 2022 issue of Science Translational Medicine as "Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies.
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Science offers a new idea of cancer: the perfect combination of genetic alterations that tumors use to promote explosive growth and prevent their own death
Time of Update: 2022-12-04
essayTPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma Dr. Jonathan Alder is an assistant professor in the Department of Pulmonary, Allergy and Critical Care Medicine at the University of Pittsburgh School of MedicineImage source: University of PittsburghScientists at the University of Pittsburgh School of Medicine have discovered the missing piece of the puzzle in the mystery of how melanoma controls its mortality.
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Powerful combination! Shenzhen Advanced Institute of the Chinese Academy of Sciences and Sai Lifu (China) jointly solve the problem of aging
Time of Update: 2022-10-03
Based on this, we will complement the advantages and resources of the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences, and will conduct more in-depth research on how to use NAD+ hydrogenation precursors such as NRH and NMNH more advanced, efficiently and safely.
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Best Crop Science is approved to produce a combination of tebuconazole and trifloxystrobin in India
Time of Update: 2021-12-24
Central pesticide tebuconazole trifloxystrobin Production License The compound trifloxystrobin product can prevent and control plant fungal diseases with a broad spectrum, and realize the long-lasting disease prevention and control that is not affected by the weather and is environmentally friendly .
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Chinese Academy of Agricultural Sciences: The combination of transcription factor MdWRKY32
Time of Update: 2021-12-24
In apple fruits treated with different temperatures, the relative gene expression levels of five members ( MdBam5 , MdBam8 , MdBam13 , MdBam15 and MdBam16 ) were induced by 20 ℃, and were significantly inhibited by 4 ℃, which was related to the starch and sugar content of the fruit.
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[Science Sub-Journal] Cupping + new crown DNA vaccine = immune response × 100, Chinese scientists
Time of Update: 2021-11-13
Researchers at Rutgers University studying COVID-19 used a suction technique similar to ancient cupping to invent a new method of delivering DNA molecules to skin cells .
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Science Signaling: In vitro chemotherapy "kills" cancer cells, combined with immunotherapy to eliminate tumors without recurrence
Time of Update: 2021-11-02
immunityOn October 19, 2021, researchers from the Massachusetts Institute of Technology published a research paper entitled "The injury response to DNA damage in live tumor cells promotes antitumor immunity" in the journal " Science Signaling " .
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of Agricultural Sciences uses electronic sensory combination algorithm technology to be used for egg identification
Time of Update: 2021-09-28
Editor in charge: Food Science 0 Recently, the monogastric animal feed innovation team of the Feed Research Institute of the Chinese Academy of Agricultural Sciences used electronic sensory analysis combined with classification algorithms to successfully distinguish different varieties and strains of eggs, providing methodological support for egg flavor research and variety identification .
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Science Sub-Journal: To "escort" tumor immunotherapy, Chinese and American scientists release the latest cancer-blocking combination therapy
Time of Update: 2021-08-07
"preclinical models" research article, the study puts forward a new direction for escorting tumor immunotherapy-the delivery of PTEN mRNA into tumor cells through lipid polymer nanoparticles can effectively induce tumor cell autophagy and release damage-related patterns Molecules (damage-associated molecular patterns, DAMPs) trigger the activation of cell death-related immunity, thereby enhancing the efficacy of ICB therapy .
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Science Sub-Journal: Combined use of low-dose radiotherapy and immunotherapy can eradicate metastatic cancer in mice
Time of Update: 2021-08-05
The relevant research results were published in the journal Science Translational Medicine on July 14, 2021, with the title of the paper "Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade" .
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Science Tranlational Medicine: To "escort" tumor immunotherapy, Chinese and American scientists released the latest cancer blocking combination therapy!
Time of Update: 2021-08-01
"preclinical models" research article, the study puts forward a new direction for escorting tumor immunotherapy-the delivery of PTEN mRNA into tumor cells through lipid polymer nanoparticles can effectively induce tumor cell autophagy and release damage-related patterns Molecules (damage-associated molecular patterns, DAMPs) trigger the activation of cell death-related immunity, thereby enhancing the efficacy of ICB therapy .
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The European Medicines Agency approves the Chinese Academy of Sciences Institute of Microbiology
Time of Update: 2021-03-21
The picture shows the monoclonal antibody combination therapy drugs, the red is LY-CoV016 jointly developed by the Institute of Microbiology of the Chinese Academy of Sciences and Junshi Biotechnology, and the black is LY-CoV555.
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Science: Strong antibody combination inhibits new coronavirus Animal experiments show protective effects
Time of Update: 2021-01-17
The results of the anti-venom experiment show that S2E12 and S2M11 and their composition of the "cocktail" can provide strong protection against the replication of the new coronavirus in animals (Photo Source: Reference 1)) For the two powerful antibodies, the researchers also made a detailed analysis, using cryo-EM to determine their role at the molecular level.
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Science: Strong antibody combination inhibits new coronavirus Animal experiments show protective effects
Time of Update: 2021-01-01
antibody S2E12 and S2M11 targeting the new coronavirus pyrethroid proteins (Photo Source: Reference 1) Animal anti-venom experiments have shown that these two antibodies can have good protective effects at very low doses.
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Zhong Nanshan: Both independent innovation and the combination of science and technology economy
Time of Update: 2020-11-28
"This is fully reflected in the whole anti-epidemic process, because the new crown pneumonia has not been encountered around the world, how it occurs, how to infect, what is the route of infection, and what causes it to become ill, how to diagnose, how to treat, how to prevent, are new things, so it is very much necessary for science and technology workers to use their creativity, innovative spirit to deal with." Zhong Nanshan said.