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Nature sub-journal Ding Chen/Hou Yingyong/Liu Tianshu/Shen Kuntang of Fudan University found
Time of Update: 2022-10-13
Further studies showed that patients with high T cell receptor signaling responded to anti-HER2-based therapy; Activation of the extracellular matrix/PI3K-AKT pathway weakens the antitumor effect of trastuzumab.
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Science sub-journal: Circadian rhythm disorders increase the risk of cancer, and body temperature plays an important role in this
Time of Update: 2022-10-12
Lamia of the Scripps Research Institute published a research paper titled Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer in Science Advances。The study revealed that the link between circadian rhythm disorders and cancer is related to body temperature, suggesting that chronic increases in signaling by members of the heat shock protein family may be a key molecular link between circadian rhythm disorders and increased cancer risk.
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Nature sub-journal: Earlier detection of lung cancer at the cellular level!
Time of Update: 2022-10-12
RELATED: Researchers at the Abramson Cancer Center at the University of Pennsylvania have found a way to identify lung cancers at the cellular level in real time during biopsies, offering hope for earlier, more confident disease detection .
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Nature sub-journal: Earlier detection of lung cancer at the cellular level!
Time of Update: 2022-10-12
RELATED: Researchers at the Abramson Cancer Center at the University of Pennsylvania have found a way to identify lung cancers at the cellular level in real time during biopsies, offering hope for earlier, more confident disease detection .
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[One case per day] Chinese Journal of Radiology: A case of primary neuroendocrine cancer of the spleen
Time of Update: 2022-10-12
Fig. 1 Ultrasound shows splenomegaly, see slightly higher echo to implement the mass, the boundary is unclear, the blood flow signal is detected, the vascular structure disorder of the spleen hilar i
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Lancet Sub-Journal (IF=45) Xu Jianmin's team at Fudan University conducted a randomized controlled
Time of Update: 2022-10-03
" Multicentre randomised controlled trial" research paper, which was randomized in China to compare surgical quality and long-term oncology outcomes of robotic and traditional laparoscopic surgery in patients with low- to medium-grade rectal cancer, and the results showed that robotic surgery has better tumor removal quality, less surgical trauma, and better postoperative recovery.
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【Nature Sub-journal】Zhu Zhenggang of Shanghai Jiao Tong University and other teams published a pangenomic analysis of gastric cancer in China
Time of Update: 2022-10-03
The researchers found that four distribution genes, ACOT1, GSTM1, SIGLEC14, and UGT2B17, exhibited extremely high deletion frequencies in gastric cancer populations.
The researchers found that four distribution genes, ACOT1, GSTM1, SIGLEC14, and UGT2B17, exhibited extremely high deletion frequencies in gastric cancer populations.
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Nature Sub-Journal: How effective is colorectal cancer targeted? New markers are predictable
Time of Update: 2022-10-02
(If you need the original text of the literature, you can add the small editor WeChat yxj_oncology to get) 1Nature sub-journal: RNF43 mutation predicts BRAFV600E metastatic colorectal cancer response to BRAF/EGFR combination therapy▎ Clinical Questions: Anti-BRAF/EGFR therapy was recently approved for the treatment of BRAF V600E metastatic colorectal cancer (mCRCBRAF-V600E), however, a large proportion of patients did not respond, which underscored the need to identify key molecules in the response to treatment.
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Lancet Sub-Journal People with diabetes are at higher risk of developing pancreatic cancer! Shi Yan
Time of Update: 2022-10-01
iNaturePancreatic cancer is one of the leading causes of cancer death worldwide and in China. Pancreatic cancer usually has a worse prognosis than most other tumors, with a 5-year survival rate of les
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Is Thyroid Cancer Required Immediate Surgery? New evidence for the JAMA sub-journal! Nearly half
Time of Update: 2022-10-01
In patients in the study who underwent an active surveillance protocol (ultrasonography every 6 months for the first 2 years and every 12 months thereafter), 41% of lesions narrowed, while no cases developed lymph node or distant metastases.
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Nature Sub-Journal: Shanghai Jiaotong University publishes Chinese pan-genomic analysis of gastric cancer
Time of Update: 2022-10-01
Recently, Zhu Zhenggang, Yu Yingyan, Chen Hongzhuan, Wei Chaochun of Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine published a research paper titled "Pangenomic analysis of Chinese gastric cancer" in Nature Communications.
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Lancet Sub-Journal (IF=17) Chinese Medical University Professor Wu Qijun Team: A systematic review
Time of Update: 2022-09-30
Reference message: —END—content is [iNature]In recent years, the team of Professor Wu Qijun of Shengjing Hospital affiliated to China Medical University has carried out a series of studies on the etiology, diagnosis and prognostic factors of ovarian cancer patients.
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Nature Sub-Journal: Why Exercise Prevents Cancer? Exercise metabolism of lactic acid, can enhance anti-cancer immunity
Time of Update: 2022-09-30
The study shows that lactic acid can increase the number of tumor-infiltrating CD8+ T cells and enhance anti-tumor immunity, and this finding is expected to be used to develop new strategies to enhance the anti-tumor effect of cancer immunotherapy.
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Cell Sub-Journal: Simulated fasting can reshape the body's immunity and improve the effect of cancer immunotherapy
Time of Update: 2022-09-22
Compared with other experimental groups, fasting simulated diet combined with immunotherapy also increased the expression of cytotoxic activity-related genes and CD8 T cell activation percentage in tumor immune infiltration.
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Nature Sub-Journal: A New Marker of Cancer Immunotherapy Response
Time of Update: 2022-09-21
"Understanding the T cell phenotype of CAR-T cells before and after infusion gives us insight into why patients respond or not to this potential life-saving therapy," said Catherine Wu, co-senior author of the study and a member of the Broad Institute, a professor of medicine at Harvard Medical School, and attending physician at Dana-Farber and Brigham Women's Hospital.