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Express $130 million to help develop an innovative drug discovery platform for undruggable targets
Time of Update: 2023-02-03
com/companynews/belharra-therapeutics-debuts-with-130-million-in-funding/ Belharra's integrated chemical proteomics-based drug development engine overcomes the limitations of traditional high-throughput screening by exploring protein/ligand interactions in the cell's natural environment through a unique library of photoaffinity-based chemical probes.
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Novo Nordisk and Microsoft jointly develop AI models to facilitate the discovery and development of new drugs
Time of Update: 2022-10-03
Novo Nordisk announced a new strategic partnership with Microsoft that combines Microsoft's computing services, cloud technology and artificial intelligence (AI) with Novo Nordisk's drug discovery, d
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Empowering new drug discovery researchers to develop the first rat model that fully mimics human AD
Time of Update: 2022-02-26
Through a head-to-head comparison study with AppNL-GF mice, Professor Lu Bai's team pointed out that from the persistent death of nerve cells and the resulting brain atrophy, as well as tau protein pathology, another key feature of Alzheimer's disease, etc.
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5 latest developments in Fragment Drug Discovery (FBDD)
Time of Update: 2021-12-25
Researchers used computational methods to design molecular fragments, link them together, and bind to different positions of SARS-CoV-2-M at the same time, and then screened a library of nearly 200,000 fragments targeting the protease binding cavity, any combination Adjacent high-affinity fragments will be connected to generate the final new candidate molecule .
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Targeting difficult-to-drug targets US$50 million to help develop next-generation small molecule discovery platforms
Time of Update: 2021-09-13
Jnana's pilot project aims to reduce the level of Phe in the blood that drives the pathology of PKU disease by inhibiting SLC6A19, so as to provide a new oral small molecule therapy for the treatment of PKU .
Retrieved August 18, 2021, from https:// therapeutics-closes-50-million-series-b-financing-to-advance-lead-pku-program-and-small-molecule-pipeline-based-on-next-gen-chemoproteomic-platform/
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Scientists are expected to develop new drug discovery strategies for "drug-free" drug targets
Time of Update: 2021-01-23
This approach has the possibility of using the power of a large number of complex chemical diversity in the DNA-coded chemical library to facilitate the discovery of membrane proteins, a technique that is an effective tool for charactertation of mating-target interactions and may in the future lead to new revelations in the development of high-volume screening methods to facilitate the capture of membrane proteins.
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New discovery of tuberculosis pathogenic mechanism provides new targets for drug development
Time of Update: 2020-05-31
Data show that for 40 years, TB treatment drugs limited to isoniazid, lifu equality is known as the "little miga rifle" several combinations, with the use of older drugs in the world for many years a
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New discovery of tuberculosis pathogenic mechanism provides new targets for drug development
Time of Update: 2020-05-31
Data show that for 40 years, TB treatment drugs limited to isoniazid, lifu equality is known as the "little miga rifle" several combinations, with the use of older drugs in the world for many years a
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Nat commun: discovery of neuroblastoma oncogene will help target new drug development
Time of Update: 2019-08-05
August 5, 2019 / bioin / - neuroblastoma accounts for 15% of all cancer deaths in children The survival rate of patients with high-risk neuroblastoma was 50% For the first time, researchers at the Aus
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the research and development cycle of new drugs at 2018 innovation drug discovery Summit Forum
Time of Update: 2018-10-22
"The target of disease is like a lock New drug development is to find the key to unlock the lock." On October 19, at the 2018 International Summit Forum on the frontier and practice of innovative drug
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Special issue of SLAs discovery: application status of high throughput flow cytometry in drug development
Time of Update: 2018-07-24
July 24, 2018 / BIOON / - a special issue of SLAs discovery introduced the latest application of high-throughput flow cytometry (HTFC) in drug development Alexandre Chigaev, The special issue of Unive
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Focus on new ideas and discoveries in antibody research and development -- 2018 new antibody drug Forum
Time of Update: 2018-06-12
Antibody drug is one of the fastest growing biological drugs, which has achieved great success in clinical and commercial fields However, there are also some problems that can not be ignored, such as