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A new type of crystal structure of abc transporter LptB2FG membrane protein complex.
Time of Update: 2020-09-07
Huang Yihua's team in 2014 analyzed the high-resolution crystal structure of 2.4 E of the membrane protein complex LptD-LptE, which is responsible for transporting and assembling lipid polysaccharies on bacterial outer membranes, and initially clarified the molecular structure of how lipid polysaccharid molecules enter the outer membrane of bacteria (Nature, 2014).
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Advances in the study of the structure of cas13a (also known as C2c2), a VI-type CRISPR-Cas system-effect protein.
Time of Update: 2020-08-27
On July 27th Cell, a leading international journal, published online new advances made by Wang Yanli and Zhang Xinzheng of the Institute of Biophysics of the Chinese Academy of Sciences in the structural study of the VI-TYPE CRISPR-Cas system-effect protein Cas13a (also known as C2c2).
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Nat Commun: Breakthrough! Scientists have successfully described the fine structure of viral
Time of Update: 2020-08-27
August 7, 2020 // -- In a study published in the international journal Nature Communications, scientists from the Czech Academy of Sciences and other institutions have described a new strain of SARS-C
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Multi-stage controlled structure of DNA-protein complex.
Time of Update: 2020-08-09
in response to this challenge, Wang Qiangbin, a researcher at the Suzhou Institute of Nanotechnology and NanoBionics of the Chinese Academy of Sciences, based on previous work (ACS Nano, 2018, 12,1673-1679; Adv.Mater., 2017, 29, 1606533; J.Am.Chem.Soc., 2016, 138, 1764-1767; Small, 2016, 12, 4955-4959; J.Am.Chem.Soc., 2015, 137,457-462; J.Am.Chem.Soc., 2013, 135,11441-11444.), the first time using viral protein and genomic RNA intrinsic mechanism to design an in-situ controlled assembly system on the DNA stent, demonstrated the multi-stage controlled structure of the DNA-protein complex.
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The near-atomic resolution structure of the visual recrimson and the inhibitory G protein complex was analyzed by the frozen electron mirror technology.
Time of Update: 2020-08-09
The cross-cutting team led by Xu Huaqiang, a researcher at the Shanghai Institute of Pharmaceutical Research of the Chinese Academy of Sciences, jointly attacked the major scientific problems in the field of cell signal transduction by successfully analyzing the near-atomic resolution structure of Rhodopsin and the inhibitory G protein (Gi) complex using cryoscopic electron sclier technology.
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The tau protein fiber structure of Pike's disease is described.
Time of Update: 2020-08-08
Scientists at the University of Cambridge used cryoscopic mirrortechnolog to detail the tau protein fibrous structure of Pike's disease, according to a neuroscience study published in the British journal Nature.
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Exploring the structure of viral proteins can help develop targeted drugs.
Time of Update: 2020-08-04
The prediction of AlphaFold's protein structure of the new coronavirus is a structural reconstruction that is separatefrom the experiment. the accuracy of the predictions, peer review and validation
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Science cover story : New crown virus protrusion protein structure and ACE2 receptor structure.
Time of Update: 2020-07-22
Novel coronavirus pneumonia virus ( ) virus spike protein (gray) is associated with receptors on human cell surface (ACE2, deep pink), which makes new crown pneumonia virus able to infect human cells.
The novel coronavirus pneumonia / new crown virus research papers, editorials and news are free to the public.
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Nat Commun: A beta protein structure reveals its toxicity
Time of Update: 2020-07-15
, July 2, 2020 /PRNewswire/ --- -- The brains of millions of people with Alzheimer's disease (AD) are slowly and inevitably running out of neurons, leading to a characteristic loss of memory and cogn
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Alzheimer's disease key protein sits in brain with different structures, nature finds
Time of Update: 2020-06-01
Today, a study published in the journal Nature Communications reveals an interesting finding: beta-amyloid proteins used in the lab are structurally distinct from beta-amyloid proteins in the brains o
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Taste-related protein structure revealed! will provide targets for drugs for the treatment of neurological diseases
Time of Update: 2020-05-31
The near-atomic horizontal structure of calcium stabilizing regulator 2, which plays a role in taste treatment and reducing brain cytotoxicity Picture: Dr Wei L?and Dr Juan Du Scientists at the Van A
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Major achievements of Science: analyze the structure of S protein of new coronavirus and assist in vaccine research and development
Time of Update: 2020-02-24
Author: as Wang zhaoyue said, "know yourself and know your enemy, and you will never lose a hundred battles." Novel coronavirus pneumonia spread in China and the world has aroused widespread concern,
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The three-dimensional structure of the complex of non visual repressor protein and GPCR was successfully resolved
Time of Update: 2020-01-02
Recently, Xu Huaqiang group, Yu Xuekui group and Congyao group of national protein science center of Shanghai Institute of Biochemistry and cell (Shanghai) made great progress in GPCR transmembrane si
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Taste related protein structure revealed! It will provide targets for drugs to treat nervous system diseases
Time of Update: 2019-12-05
Understanding how the brain processes sweetness, bitterness and freshness may help researchers design more effective drugs for nervous system diseases Calcium homeostasis regulator 2 has a near atomic
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Nat commun: a β protein synthesized in vitro is different from brain-derived a β protein of Alzheimer's disease in structure
Time of Update: 2019-11-17
November 17, 2019 / Biovalley BIOON / - -- Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the deposition of a β amyloid fibrils (also known as a β fibrils) and ta