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Nature Sub-Journal: After recovering, still immunodeficiency, what does the new coronavirus do to B cells?
Time of Update: 2021-09-29
These results indicate that SARS-CoV-2 infection may change the metabolic activity of b cells and increase the production of ROS, thereby reducing the expression of CD19 and bcr-dependent signal transduction .
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CELL HOST MICROBE: What are the microbiomes involved in early colorectal cancer?
Time of Update: 2021-09-28
Other analyses have shown that the fragile bacteria from polyp patients are bft-negative, activate NF-κB through Toll-like receptor 4, induce pro-inflammatory responses , and are rich in genes related to LPS biosynthesis .
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What is the magic of this cell therapy to make the tumors of patients with advanced lung cancer disappear completely?
Time of Update: 2021-08-27
Lung cancer is one of the leading causes of cancer deaths in the world, and about 85% of them are non-small cell lung cancer (NSCLC) . In recent years, the development of PD-1 inhibitors has allowed
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Summary of treatment options for renal cell carcinoma: what is the current situation and what is the future?
Time of Update: 2021-08-08
Rapalogs (analogs of rapamycin), everolimus and temsirolimus are the most common mTOR inhibitors and have been shown to have potent anticancer activity against several tumor types including RCC (Figure 2b) .
VEGFR signaling and mTOR are important targets, and several approved drugs have significantly improved the survival rate of RCC patients .
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Cell Journal: What determines your appetite, is it your belly?
Time of Update: 2021-06-08
Recently, a new study published in a sub-Journal of Cell shows that the intestinal-brain communication of different sensory neurons controls eating and glucose metabolism in different ways .
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Focusing on the diagnosis and treatment of small cell lung cancer, what kind of spark will come from radiotherapy and immunotherapy?
Time of Update: 2021-04-23
Professor Bi Nan: Some studies have found that some patients with extensive-stage small cell lung cancer have benefited from OS after chest radiotherapy.
Professor Song Yongchun: For patients with small cell lung cancer, radiotherapy is a very important treatment, but it is also necessary to pay attention to complications, such as pneumonia.
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What are the focus of non-clinical research and evaluation of CDE's release of genetically modified cell therapy products?
Time of Update: 2021-03-24
Knowing that, this article interprets several related issues in the "Technical Guidelines for Non-clinical Research and Evaluation of Gene Modified Cell Therapy Products".
). (Source: "Technical Guidelines for Non-clinical Research and Evaluation of Gene Modified Cell Therapy Products") 2.
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Cell: Under what circumstances will the iron in our body rise?
Time of Update: 2021-03-18
What is the reason?On February 18, 2021, the international academic journal Cell published an online study titled "A role of PIEZO1 in iron metabolism in mice and humans" by the Ardem Patapoutian team of the Howard Hughes Medical Institute in the United States.
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Cell: Special hormones in the brain may help uncover what exercise can do to improve the body's metabolism...
Time of Update: 2021-03-08
researchers said that mice with mild mitochondrial stress in POMC neurons may avoid obesity due to changes in body adipose tissue, while mice with partially missing Crif1 gene function showed more heat production and an in-depth analysis of fat cells in their bodies, and found increased levels of brown fat cells in their bodies.
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ASCO GU 2021: What is the effectiveness of immunotherapy in the first line of metastatic renal cell carcinoma?
Time of Update: 2021-02-24
Gan provided the following concluding statement for the presentation: Although the immunotherapy/VEGF inhibitor combination has a longer duration of treatment and a higher objective response rate, there is no difference between the total survival rate and the next treatment time between the nivolumab plus ipilimumab combination and the immunotherapy/VEGF inhibitor combination in the IMDC moderate/low-risk population.
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Eur Radiol: What exactly is liver cell liver cancer without fast-forwarding and fast-out?
Time of Update: 2021-01-30
The qualitative diagnosis of hepatocellular liver cancer (HCC) does not require biopsy to a great extent, and the qualitative diagnosis can be achieved by relying solely on imaging characteristics. a
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Cell Metab: The world is "anti-sugar" to see what cell sub-journals say
Time of Update: 2021-01-16
high fructose promotes the proliferation of leukemia cells, the researchers tested the expression levels of metabolic enzymes and GLUT5, the main fructose transporter.
in addition to low GLUT5 leukemia cells relying on SSP under fructose-rich conditions, the researchers also found that normal hematocytes/progeny cells did not observe changes in SSP fluform under fructose-rich conditions.
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PRSB: What's new! Cancer cells may be able to spread more efficiently to their surroundings!
Time of Update: 2020-12-20
Unlike human health cells, cancer cells are thought to lose their ability to perceive things around them early in their progression, meaning they are better able to "blindfold" and focus on replicating and forming primary tumors, and for the first time in this paper, researchers have observed that some cancer cells can actually re-open that awareness and remove "eye masks" to effectively move to other parts of the body for proliferation.
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Cell Rep: What's new! Scientists identify motor neurone disease risk genes in "junk DNA"!
Time of Update: 2020-12-19
4, 2020 // -- In a recent study published in the international journal Cell Reports, scientists from the University of Sheffield and others identified a new risk factor for motor neurone disease (MND,
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Sci Transl Med: What's new! The body's stress hormones may promote sleeping cancer cells to wake up and cause the cancer to return!
Time of Update: 2020-12-19
December 5, 2020 // -- In a recent study published in the international journal Science Translational Medicine, scientists from the United States, Germany and other countries jointly found that natural stress hormones may reactivate dormant cancer cells in mice, and that the results may help develop new treatments for cancer.