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BJH: allogeneic hematopoietic cell transplantation in patients with relapsed/refractory anaplastic large-cell lymphoma

 Last Update: 2022-09-30
 Source: Internet
 Author: User

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Anaplastic large cell lymphoma (ALCL) is a T-cell/Zero cell line (NHL) of CD30+ invasive non-Hodgkin lymphoma (NHL), which accounts for 2%
of all NHL in adults.

Therefore, a research team used the observational database of the International Center for Blood and Bone Marrow Transplantation Research (CIBMTR) to assess the prognosis
of allogeneic-HCT in patients with ALCL.

Figure 1: Allogeneic hematopoietic cell transplant results
for anaplastic large-cell lymphoma.

Figure 2: Effect
of disease status on transplant outcomes.

About multivariate regression analysis of African American ethnicity (risk ratio [HR] 2.

Overall, these data suggest that allo-HCT can achieve lasting disease control
in a significant proportion of patients with R/R ALCL.

Original Source:

Furqan, F, Ahn, KW, Chen, Y, Kaur, M, Abutalib, SA, Ahmed, N, et al.

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