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    Home > Active Ingredient News > Blood System > Choose the bottom of the spicy pot or the bottom of the tomato pot?

    Choose the bottom of the spicy pot or the bottom of the tomato pot?

    • Last Update: 2021-01-15
    • Source: Internet
    • Author: User
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    Pixabay's recent weather is getting colder and colder, the men of the north can't carry the winter of the south, warm-up artifacts are nothing but a red hot hot pot.
    it is understood that chili peppers from the end of the Ming people in China, initially only to watch crops and medicine.
    , according to Food Herbs, chili peppers warm the spleen and stomach.
    if the cold appears vomiting, diarrhea, stomach pain and other symptoms, you can eat some peppers appropriately.
    since entering Chinese recipes, there has been a hot trend in China, with the most spicy provinces located in the upper and middle reaches of the Yangtze River, including Hunan, Hubei, Jiangxi, Guizhou and Sichuan.
    saying, "Sichuan people are not afraid of spicy, Guizhou people are not afraid of spicy, Hunan people are afraid of not spicy, Hubei people are not hot afraid."
    as scientists continue to study chili peppers, chili peppers can not only be an essential condiment in people's daily lives, but also play an important role in the health of the body.
    A recent study published in the journal Nature showed that spicy foods activate damage to the receptor nerves, which in turn promotes blood stem cell mobilization in the bone marrow, replenishes blood cells and maintains normal physiological function, a finding that has a positive effect on stem cell transplantation.
    Anastasia N. Tikhonova & Iannis Aifantis.Pain-sensing neurons mobilize blood stem cells from bone marrow.nature.Using immunofluorescence imaging, the researchers studied nerve cells in the bone marrow of mice and found that while epinephrine fibers from the sensory nervous system regulate hematopoietic stem cell mobilization, the vast majority (about 77 percent) are regulated by injury receptor neurons labeled by the calcitonin gene-associated peptide (CGRP).
    analysis of the total length of nerves per unit area of bone marrow showed that CGRP and anti-tyrosine hydroxyase (TH) nerves had similar lengths, suggesting that both CGRP and TH nerves showed similar effects in bone marrow.
    -sensing nerve cells regulate the mobilization of hematopoietic stem cells. Pain neurons promote hematopoietic stem cell mobilization. To study the potential role of injured sensory neurons in maintaining hematopoietic neurons, the researchers used drugs and genetic engineering to knock out the cross-sensing nerve and the injury-affected nerve, and found that this had no effect on the maintenance of hematopoietic stem cells, but the mobilization of hematopoietic stem cells decreased significantly, which means that injury-receptor nerves can affect the adhesion or migration of hematopoietic stem cells.
    CGRP of the nerve center induces hematopoietic stem cell mobilization through its 1ogeneic subject CALCRL-RAMP1. Subsequently, after treating mice with granulocyte collection stimulation factors (G-CSF) and plerixafor, CGRP was given to significantly improve hematopoietic stem cell mobilization, and CGRP could directly affect hematopoietic stem cells.
    , researchers found that CGRP could significantly improve hematopoietic stem cell mobilization by treating genetically engineered mice with five rounds of chemotherapy a week.
    then, spicy food activates the damage to the receptor nerve, can it improve hematopoietic stem cell mobilization by raising CGRP levels? The researchers looked at CGRP levels by feeding foods rich in capsaicin.
    found that spicy foods increased CGRP levels in extracellular fluids in bone marrow and improved hematopoietic stem cell mobilization induced by CGRP.
    pepper as one of the five tastes of life, like people enjoy it, annoying people but avoid it.
    at home and abroad have indicated that eating chili peppers has great benefits for the health of the body.
    researchers have recently found that chili peppers not only extend their life, but also prevent cardiovascular disease.
    a 2020 scientific meeting of the American College of Cardiology, scientists from the Cleveland Clinic report that eating chili peppers may lead to longer life and a significantly reduced risk of dying from cardiovascular disease or cancer.
    !/9144/presentation/39489 Researchers screened 4,729 studies from five global health databases and collected health and dietary records of more than 570,000 participants from four countries, including the United States, Italy, China and Iran, to analyze the health outcomes of people who ate red peppers.
    study found that people who ate red peppers had a 25 percent lower total mortality rate, a 23 percent lower cancer death rate, and a 26 percent lower cardiovascular mortality rate than those who ate little or no red peppers.
    of chili peppers reduces the associated mortality from a variety of diseases. The researchers say the frequent intake of red peppers is directly related to all-cause mortality, cardiovascular disease mortality and reduced cancer mortality, perhaps underscoring the important role diet plays in the health of the body.
    , however, this study does not accurately say that eating more red peppers can help prolong life and reduce the risk of death, especially cardiovascular disease or cancer.
    However, a study from Italy, published in the journal JACC, looked at the intake of chili peppers, which included a total of 22,811 participants, and collected the frequency of eating chili peppers through questionnaires, divided the frequency of eating chili peppers into four groups of "no eating", "no more than twice a week", "2-4 times a week" and "more than four times a week" and followed up for up to 8.2 years.
    study showed that people who ate red peppers more than four times a week had a 23 percent and 34 percent lower risk of cardiovascular death, respectively, than those who never ate or rarely ate red peppers (less than twice a week).
    addition, regular intake of chili peppers was associated with a negative risk of isoemia heart disease and cerebrovascular death.
    in individuals without high blood pressure, the correlation between eating chili peppers and all-cause mortality appeared to be stronger.
    it's worth noting that even if the diet is generally unhealthy, eating chili peppers can benefit.
    , why does chili have such magical power? The scientific community now attributes this mainly to capsaicin in chili peppers.
    is a synthetic derivative of herbamine with spicy irritants, and is an alkaloid containing vanillaamide.
    natural capsaicin consists of capsaicin, hydrogen-dehydro capsaicin, low-hydrogen capsaicin, high-bihydro-capsaicin and high-capsaicin series of similar species.
    , 19 capsaicin isotopes have been found, all of which are similar in structure to capsaicin.
    , the most widely studied capsaicin subject is TRPV1 and one of the most concerned non-selective cation channel subjects.
    Dreamtime.com TRPV1 is widely distributed in mammalian sense nerve fibers, especially myelin-free C and some of the less myelin fibers, expressed in the central nervous system, perional nerves, breathing, digestion, cardiovascular and urinary systems.
    addition, TRPV1 has many biological functions, including participation in immune activation, mediated inflammatory pain, participation in the regulation of body temperature, regulation of gastrointestinal function, regulation of fat production, and participation in the physiological and pathological processes of a variety of tumors.
    In recent years, as scientists continue to study capsaicin, capsaicin not only has a variety of pharmacological effects, such as analgesics, itching, anti-inflammatory, antioxidant and blood pressure regulation, in animal experiments, but also can inhibit the growth of a variety of malignant solid tumors.
    study published in the journal Nature Medicine shows that capsaicin can signal through the capsaicin-like subject TRPV1, which is highly expressed in malignant gliomas, a brain cancer that signals and activates a strengthened path in cancer cells to cause cancer cells to die.
    and the researchers found that the signals sent by the capsaicin-like subject TRPV1 could be used as a drug target for brain tumors as a candidate path.
    you can't imagine that eating chili peppers has many similarities to eating marijuana.
    published in the journal PNAS, "Endocannabinoid system acts as a regulator of immune homeostasis in the gut". The results show that capsaicin binds to TRPV1 subjects on the cell surface, further triggering cell production of cannabinoids.
    cannabinin is a substance very similar to the chemical structure of the active ingredient in cannabis, which can reduce the activity of the immune system.
    , the researchers also found that we feel hot when we chew chili peppers, but that's not the case.
    capsaicin in chili peppers can bind to specific subjects that trigger a burning sensation in the brain, and these are spread throughout the gastrointestinal digestive tract, solving a long-standing mystery.
    of course, chili peppers can also have a negative effect.
    study, published in the journal Nutrients, entitled "High Chili Intake and Cognitive Function 4582 Adults: An Open Cohort Study Over 15 Years", looked at the relationship between chili intake and cognitive function in 3,302 Chinese adults and showed that people who ate more spicy foods had lower cognitive abilities.
    addition, capsaicin itself is highly irritating and can stimulate the mucous membranes to cause a series of symptoms such as sneezing, nosebleeds, coughing, bronchial contractions and difficulty breathing.
    addition, although capsaicin benefits a lot, but the health of the diet depends more on the overall balance of the match, do not have to eat spicy or do not eat spicy and tangled.
    people's tolerance to food is also different, can not absolutely judge how much spicy food is healthy.
    need to be eaten properly, not too much.
    Source: Met Medical Comprehensive Report Milly Source: MedSci Original Copyright Notice: All text, images and audio and video materials on this website that indicate "Source: Mets Medicine" or "Source: MedSci Originals" are owned by Metz Medicine and are not authorized to be reproduced by any media, website or individual, and must be reproduced with the words "Source: Mets Medicine".
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