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Hope for the future? Ferritin nanoparticle vaccines protect against all SARS-CoV-2 variants
Time of Update: 2023-02-02
The author is the inventor of Stanford University and Chan Zuckerberg Biohub patenting immunogenic coronavirus fusion proteins and related methods, which have been licensed to Vaccine Inc. While the rapid development of COVID vaccines is a scientific victory, there is still a need for a globally available vaccine that can provide lasting immunity against current and future SARS-CoV-2 variants (VOCs).
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on the application of ferritin nanocarriers in the field of nutrition and health
Time of Update: 2022-11-14
The coupling and modification of some functional groups on the outer surface of ferritin can give it characteristics such as luminescence imaging, the inner surface is mainly used as a nanoreactor to synthesize inorganic nanomaterials or for embedding active nutritional small molecules, and the interunit interface can be used to regulate the dissociation and recombination of ferritin molecules and design new cage-like proteins.
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Du Yongzhong's research group of the School of Pharmacy of Zhejiang University reported in Advanced Materials that ferritin targeted prodrugs are used for...
Time of Update: 2022-10-31
Schematic diagram of ferritin-targeted prodrug nanoparticles and their anti-tumor mechanisms for synergistic PDT and iron death therapyThe first author of this paper is Zhu Luwen, a doctoral student at the School of Pharmacy, Zhejiang University, Professor Ji Jiansong, School of Medicine, Zhejiang University, Professor Du Yongzhong, School of Pharmacy, Zhejiang University, and Xu Xiaoling, associate researcher of Zhejiang Shuren University.
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Acta Haematol: Serum ferritin threshold differentiates patients at higher risk of increased
Time of Update: 2022-03-05
PLT was significantly increased in the low s-ft group (*;PMultivariate analysis showed that PLT rate of change was associated with serum ferritin (s-ft) and red blood cell (RBC) counts [β coefficient; 0.
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Rising star: 'pan' COVID-19 ferritin nanoparticle vaccine
Time of Update: 2022-01-25
A series of recently published preclinical studies have shown that the spike ferritin nanoparticle (SpFN) COVID-19 vaccine developed at the Walter-Reed Army Research Institute (WRAIR) in the United States not only elicits an effective immune response, but also May offer broad protection against worrying variants of SARS-CoV-2 and other coronaviruses .
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New breakthrough in traditional Chinese medicine: ferritin "wrapped" arsenic targeted treatment of leukemia
Time of Update: 2021-11-13
A new research result participated by the Department of Hematology, Zhujiang Hospital of Southern Medical University, puts forward the latest treatment strategy for targeted "bionic delivery" of arsenic agents, which is expected to enter the clinic in the future, improve the curative effect and scope of application of leukemia, and reduce its toxic side effects .
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Nanomedicine based on ferritin for targeted leukemia treatment
Time of Update: 2021-11-01
Image: CD71 expression in leukemia cells, construction of As@Fn and analysis of targeting ability Researchers from the Institute of Process Engineering of the Chinese Academy of Sciences, Peking University and Zhujiang Hospital of Southern Medical University have developed a ferritin (Fn)-based nanomedicine for targeted delivery of arsenic (As) and effective treatment of multiple types of leukemia .
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Ferritin may become a marker for the diagnosis, differential diagnosis and prognosis of IrAEs
Time of Update: 2021-08-26
When adverse events occurred in the irAE group, the ferritin content (normal range 35-150μg/L) rose from the baseline value of 86μg/L to the median value of 927μg/L .
Ferritin as a diagnostic, differential diagnostic, and prognostic marker for immune-related adverse events.
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A new method for detecting autoimmune diseases by ferritin multimeric antigen-antibody
Time of Update: 2021-08-10
In order to improve the diagnosis efficiency of autoimmune diseases, the team of Academician Yan Xiyun of the Institute of Biophysics of the Chinese Academy of Sciences and the team of Professor Li Zhanguo from Peking University People’s Hospital have developed a multimeric antigen based on ferritin display and multimeric secondary antibody detection using pSS as a research model.
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Scientists have developed a new method for detecting autoimmune diseases by ferritin multimeric antigen-antibody
Time of Update: 2021-06-17
In order to improve the diagnostic efficiency of autoimmune diseases, the team of Yan Xiyun, an academician of the Chinese Academy of Sciences and a researcher of the Institute of Biophysics of the Chinese Academy of Sciences, and Li Zhanguo, a professor at Peking University People’s Hospital, developed a new method based on ferritin to display multimeric antigens and multimeric antigens using pSS as a research model.
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The team of academician Yan Xiyun collaborated to develop a new method for the detection of autoimmune diseases by ferritin multimeric antigen-antibody
Time of Update: 2021-06-11
In order to improve the diagnostic efficiency of autoimmune diseases, the team of Yan Xiyun, an academician of the Chinese Academy of Sciences and a researcher of the Institute of Biophysics of the Chinese Academy of Sciences, and Li Zhanguo, a professor at Peking University People’s Hospital, have developed a new method based on ferritin to display multimeric antigens and multipolymers.
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Researchers have developed a new method for detecting autoimmune diseases by ferritin multimeric antigen-antibody
Time of Update: 2021-06-10
In order to improve the diagnostic efficiency of autoimmune diseases, the team of Yan Xiyun, an academician of the Chinese Academy of Sciences and a researcher of the Institute of Biophysics of the Chinese Academy of Sciences, and Li Zhanguo, a professor at Peking University People’s Hospital, have developed a new method based on ferritin to display multimeric antigens and multipolymers.
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A new method for detecting autoimmune diseases by ferritin multimeric antigen-antibody
Time of Update: 2021-06-04
In order to improve the efficiency of diagnosis of autoimmune diseases, China Kexue Yuan academician , Zhong Keyuan researcher at the Institute of Biophysics Xiyun Yan teamwork with Professor People's Hospital of Peking University, Li Zhan-guo team, with pSS as a research model to develop a showcase poly-antigen based on ferritin and The new method of detecting autoantibodies by poly-second antibodies increases the sensitivity of detection by 100-1000 times.
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BMC Gastroenterology: Abnormal levels of ferritin usually indicate a poor prognosis in patients with liver cirrhosis
Time of Update: 2021-03-30
The results of the study found that the serum levels of ferritin in men and elderly patients were higher than those in women (median: 152.
002), and higher circulating ferritin levels (> 310 μg/L) in decompensated patients are associated with an increased risk of bacterial infection (sHR: 2.
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BMC Gastroenterology: Abnormal levels of ferritin usually indicate a poor prognosis in patients with liver cirrhosis
Time of Update: 2021-03-26
The results of the study found that the serum levels of ferritin in men and elderly patients were higher than those in women (median: 152.
002), and higher circulating ferritin levels (> 310 μg/L) in decompensated patients are associated with an increased risk of bacterial infection (sHR: 2.