-
Why does Alzheimer's disease destroy the brain like this? The sub-journal Science reveals the hidden mechanism
Time of Update: 2023-01-05
"We noticed that brain regions with high expression of the APOE gene are closely related to areas where tau protein is tangled and tissue damaged," Professor Gordon said, "Not only the APOE gene, but the 20 genes most closely associated with Alzheimer's disease are expressed in a similar pattern in the temporal lobe.
-
Science sub-journal: How does oil smoke induce lung cancer? Scientists have found that long-term
Time of Update: 2022-12-30
The team found that long-term inhalation of nanoscale carbon black particles of 15-75nm can lead to mitochondrial damage and metabolic reprogramming of lung macrophages, which in turn leads to increased lactic acid secretion and immunosuppressive microenvironment formation, promoting the occurrence and metastasis of lung cancer.
-
Science: How does the hippocampus selectively recruit neurons to consolidate memory?
Time of Update: 2022-11-25
During oscillations of ripples in vivoPreferential recruitment of AcD cellsRecent studies have shown significant morphological and functional inhibition between host cells in cortical networks, and found non-cellular origin (i.
-
Science does not reduce calorie intake, but it increases the underlying mechanisms of thermogenesis
Time of Update: 2022-10-25
”Time-restricted feeding mitigates obesity through adipocyte thermogenesis The researchers report that mice that ate during the active phase of the daily diurnal cycle burned more calories by enhancing thermogenesis, which slowed the progression of obesity.
-
Science & Progress: Why does Parkinson's disease progress so much differently in different patients?
Time of Update: 2022-10-13
Therefore, in the next experiments, the researchers injected a superoxide fluorescent probe (DHE) into mice abdominally based on the above model to explore the transmission pathway of neuron overactivation → peroxide production →α-Syn. The study found that in the over-activated side of the brain of neurons, there was also an increase in superoxide signaling and an increase in the spread of human-derived α-Syn, and the nitrolification level of human-α-Syn was also significantly improved.
-
Health Science Why does sugar-free cola not increase sugar, or is it not recommended for you to drink it?
Time of Update: 2022-09-08
In fact, the reason why sugar-free and sugar-sweetened beverages are "just as bad" is that sugar-free beverages may stimulate appetite and make people crave more high-sugar foods; in addition, artificial sweeteners may cause chemical reactions in fat tissue and intestinal bacteria, which can make the body poor glucose tolerance, leading to type 2 diabetes .
-
The benefits of folic acid are well known, but why does the U.S. remove a lot of folic acid supplements? A popular science!
Time of Update: 2022-09-08
Low body weight, cleft lip and palate, heart defects In addition, related studies have pointed out that folic acid has the effect of preventing cardiovascular diseases, so middle-aged and elderly people in the absence of folic acid can also take folic acid supplements appropriately according to doctors' recommendations.
-
How does an injured brain recover on its own? Science: Scientists successfully constructed
Time of Update: 2022-09-07
On September 2, 2022, BGI Life Sciences Research Institute, together with the team of Professor Fei Jifeng of Guangdong Provincial People's Hospital and the team of Professor Chen Liang of Wuhan University, published a research paper entitled "Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration" in science, a top international academic journal 。 The study mapped the first spatial-temporal atlas of salamander brain regeneration, which is also the world's first spatio-temporal atlas of brain regeneration.
-
The latest "Cell" of the University of Science and Technology of China: If this thing is missing after birth, why does it endanger the brain for life?
Time of Update: 2022-08-20
What is the neural mechanism of visual perception to promote brain development, and what are the adverse effects of lack of light on brain development?Image source: 123RF This week, in a new study published in the journal Cell, a research team led by Professor Xue Tian and Bao Jinte, a researcher at the University of Science and Technology of China, uncovered the neural mechanism by which visual perception promotes brain development .
-
"Science" How many steps does it take to accurately transform normal cells into cancer cells?
Time of Update: 2022-05-09
Single-cell RNA sequencing revealed that these cells gradually altered their gene expression programs as more genetic mutations were introduced, and that mouse tumor models had similar gene expression patterns and pigmentation patterns to human melanoma patients with the same genotype .
-
How does the warming science instrument behind the time capsule alleviate the greenhouse effect
Time of Update: 2022-03-25
Although glacier melting is affected to a certain extent by seasonal cyclical changes, a large number of examples in the past and the accumulation of large amounts of data have led to the key to the problem-the greenhouse effect.
-
"Science" How does the RNA signal of plants communicate?
Time of Update: 2022-01-24
By studying the mustard-like plant Arabidopsis thaliana, Professor David Jackson of Cold Spring Harbor Laboratory (CSHL) and his team discovered that RNA messages require a special protein to escort them where they need to go .
-
Science Sub-Journal: Does excessive intake of simple sugars affect the advanced functions of the brain?
Time of Update: 2022-01-09
Excessive intake of sucrose during adolescence can cause cell damage to non-neuronal cell populations, inhibit the uptake of glucose from the blood into the brain parenchyma, cause certain neuronal dysfunctions, and lead to the main symptoms of mental illness .
-
How long does it take for fun science running to be effective?
Time of Update: 2022-01-08
Only 10 minutes of moderate-intensity running can increase the local blood flow to different points of the prefrontal cortex (the part of the brain that plays an important role in controlling emotions and executive functions), which is beneficial to improve mental health and enhance executive ability.
-
Science︱ Does Serotonin help overcome cocaine addiction?
Time of Update: 2021-11-05
Therefore, in order to establish a causal relationship between 5-HT-induced presynaptic depression and compulsive cocaine self-administration, first, the authors specifically knocked out 5-HT1B receptors projected to DS in OFC neurons (Figure 4 A, B) .