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JAMA Neurol: The relationship between white matter hyperintensity and the pathology and progression of Parkinson's disease in the elderly
Time of Update: 2021-11-13
Brain magnetic resonance imaging (MRI) and autopsy studies have shown that in elderly people without Parkinson's disease, one or more pathological markers of cerebrovascular disease are usually related to the severity of Parkinson's disease .
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People familiar with the matter: OPEC + this week's meeting is expected to cool the oil market by increasing production
Time of Update: 2021-11-08
Although the usual differences remain (that is, Saudi Arabia is cautious and Russia is eager to relax supply), all parties are ready to increase production .
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Sub-Journal of "Nature": It doesn't matter how much you eat, the time you eat is important!
Time of Update: 2021-11-04
In order to observe the effects of "less eating" and "fasting" separately, the researchers selected a batch of C57BL/6J male mice and divided them into four groups, namely the control group (AL) and three groups of different calorie restriction diets.
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and the abnormality of gray matter volume and white matter microstructure
Time of Update: 2021-11-01
Recently, studies have explored the effect of age of onset on the microstructure abnormalities of gray matter volume (GMV) and white matter (WM) in adult patients with multiple sclerosis (MS) and its impact on the clinical phenotype and course of the disease .
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JNNP: Gray matter atrophy in multiple brain regions can be used as a predictor of the development of dementia
Time of Update: 2021-11-01
The total number of gray matter atrophy areas in the four dementia-related brain areasDuring the follow-up period, 113 participants developed all-cause dementia, of which 83 had Alzheimer's disease (AD) .
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Science explains the white matter of the brain
Time of Update: 2021-10-22
However, the Hebrew University research team was the first to use Nissl-stained brain slices to reveal fiber pathways in the white matter .
Researchers realized that by using simple computational tools in the field of image processing, they could use the pattern of cell organization to reveal the structure of white matter .
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CCSC: No matter how big or small, CAR-T is used in refractory lymphoma
Time of Update: 2021-10-21
Neelapu suggested that patients with R/R LBCL should receive Akirensai injection before the disease progresses and the tumor burden increases, in order to obtain better efficacy and safety .
In addition, the ZUMA-12 study explored the efficacy and safety of Akirensai injection in the first-line treatment of high-risk LBCL .
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JAHA: The effect of peripheral microvascular endothelial dysfunction on white matter hyperintensity
Time of Update: 2021-10-20
Peripheral endothelial dysfunction is associated with the increase in the volume of paracortical WMH in patients over 50 years of age, which is a potential marker for predicting the risk of IS in the future .
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Impaired white matter integrity in patients with Alzheimer's disease gene mutations
Time of Update: 2021-10-19
Prescott and his colleagues on patients with sporadic Alzheimer’s disease (accounting for 99% of cases) found that as the burden of amyloid protein in patients increases, through a method called diffusion tensor imaging (DTI) MRI technology measurement, the connectivity of the white matter structure is significantly reduced,Jeffrey R.
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JNNP: Longitudinal changes in thalamic white matter and gray matter related to visual hallucinations in patients with Parkinson's disease
Time of Update: 2021-10-09
Visual hallucinations (VH) are common in Parkinson’s disease (PD) and can cause severe suffering to affected individuals and their families, leading to worse results: patients with Parkinson’s disease
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JNNP: The gray matter changes of the thalamus can reflect the visual hallucinations of Parkinson's patients
Time of Update: 2021-10-09
The important significance of this study lies in the discovery: PD hallucinations show white matter loss, especially in the posterior connection and the thalamic nucleus, and the thickness of the cortex is relatively preserved over time .
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Mov Disord: What is the basis of the gray matter structure of progressive supranuclear palsy and speech disorder?
Time of Update: 2021-09-29
Clark and others of the Mayo Clinic in the United States explored the relationship between gray matter volume and white matter duct integrity, oral and pharynx dysphagia, and airway invasion .
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Stroke: White matter high signal burden and collateral circulation in patients with large vessel occlusive stroke
Time of Update: 2021-09-18
Cardiovascular Thrombosis Stroke The researchers enrolled patients with acute ischemic stroke who had continuous visits for endovascular thrombus removal from January 2015 to December 2017 due to anterior circulation and large blood vessel occlusion, and were recovered by fluid attenuation inversion-semi-automatic volume of magnetic resonance imaging The analysis evaluates the WMH volume (periventricular, deep and total volume) .
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What matters should be noted when minors are vaccinated against the new crown vaccine?
Time of Update: 2021-09-10
In June of this year, the world-renowned journal "The Lancet-Infectious Diseases" published online the safety and tolerability of the new coronavirus inactivated vaccine developed by Kexing in healthy children and adolescents aged 3 to 17 in China And immunogenic double-blind randomized controlled phase I/II clinical study results .
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Size doesn't matter: It is difficult to evaluate the efficacy of anticancer drugs when the tumor shrinks
Time of Update: 2021-09-05
Although our understanding of the molecular mechanisms of tumor treatment continues to deepen, the early drug evaluation system still needs a lot of work to improve the prediction of OS, the most critical therapeutic target .